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15 handpicked stocks

MASH Drug Developers Could Attract M&A in 2025

Roche's $3.5 billion deal to acquire 89bio for its late-stage liver disease drug highlights the immense commercial potential seen in the MASH treatment landscape. This move could trigger a wave of investment and further acquisitions, benefiting other biotech firms with promising therapies for metabolic disorders.

Author avatar

Han Tan | Market Analyst

Published on September 19

Your Basket's Financial Footprint

Market capitalisation breakdown for the MASH Drug Developers basket, showing total and per-stock market caps.

Key Takeaways for Investors:
  • Large-cap concentration suggests generally lower volatility and more stable returns, so performance will likely track broad market trends.
  • Use this basket as a core portfolio holding for diversified exposure, not as a speculative or short-term trade.
  • Expect modest, steady long-term appreciation rather than rapid, explosive gains; growth is likely gradual.
Total Market Cap
  • MDGL: $9.58B

  • SGMT: $323.22M

  • ETNB: $2.20B

  • Other

About This Group of Stocks

1

Our Expert Thinking

Roche's massive $3.5 billion acquisition of 89bio for its MASH drug signals a pivotal moment in liver disease treatment. This premium purchase reflects the immense commercial potential pharmaceutical giants see in metabolic dysfunction therapies, where few approved treatments exist for a large patient population.

2

What You Need to Know

These are primarily clinical-stage biopharmaceutical companies developing novel therapies for liver and metabolic diseases. The sector focuses on complex pathways targeting MASH and related conditions, representing a high-growth area with significant unmet medical need and potential for consolidation.

3

Why These Stocks

Each company was selected for its promising drug candidates in MASH and cardiometabolic conditions. Following Roche's strategic move, these firms may become attractive M&A targets, potentially benefiting from heightened investor interest and acquisition activity in this therapeutic space.

Why You'll Want to Watch These Stocks

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M&A Target Potential

Roche's massive acquisition premium could spark a wave of similar deals. These biotech firms with promising MASH therapies may become attractive takeover targets for pharmaceutical giants seeking to enter this lucrative market.

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Breakthrough Treatment Market

MASH affects millions globally with few approved treatments available. Companies developing effective therapies for this progressive liver disease could capture significant market share in an underserved therapeutic area.

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Clinical Milestone Catalysts

These clinical-stage companies are advancing novel treatments through trials. Positive data readouts or regulatory approvals could trigger substantial share price movements and increased investor attention.

Get the full story on this Basket. Read our detailed article on its risks and potential.

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