
Alnylam Pharmaceuticals, Inc.
Alnylam Pharmaceuticals (ALNY) is a biotechnology company that develops RNA interference (RNAi) therapeutics to silence disease-causing genes. Investors should know it has moved from research-stage to a commercial entity, with multiple approved medicines for rare genetic disorders — including treatments for hereditary ATTR amyloidosis, acute hepatic porphyria and primary hyperoxaluria — and a broad pipeline built on its GalNAc delivery platform. The business is growth-oriented: revenues depend on uptake of marketed drugs, pricing and successful launches of late-stage candidates. Key risks include trial outcomes, regulatory decisions, pricing pressures, manufacturing scale-up and competition from other modalities. With a market capitalisation near $62.13 billion, Alnylam may appeal to investors seeking exposure to innovative therapeutics, but it suits those comfortable with biotech volatility. This is general information for educational purposes only and not personalised investment advice; values can fall as well as rise.
Why It's Moving

Alnylam Unveils Ambitious 'Alnylam 2030' Strategy, Eyeing Explosive Growth in RNAi Therapeutics
- 2025 net product revenues hit $2.987 billion, up 81% year-over-year, fueled by 103% surge in TTR revenues from Amvuttra, underscoring robust demand for flagship treatments.
- 2026 revenue guidance set at $4.9-$5.3 billion, implying 71% growth at midpoint, with plans for next-gen nucresiran launch by 2028 in polyneuropathy to dominate TTR market.
- Pipeline acceleration includes Phase 1 data for obesity drug ALN-2232 and three-to-four new IND filings by 2026 end, plus 30% of sales reinvested in R&D for sustainable breakthroughs.

Alnylam Unveils Ambitious 'Alnylam 2030' Strategy, Eyeing Explosive Growth in RNAi Therapeutics
- 2025 net product revenues hit $2.987 billion, up 81% year-over-year, fueled by 103% surge in TTR revenues from Amvuttra, underscoring robust demand for flagship treatments.
- 2026 revenue guidance set at $4.9-$5.3 billion, implying 71% growth at midpoint, with plans for next-gen nucresiran launch by 2028 in polyneuropathy to dominate TTR market.
- Pipeline acceleration includes Phase 1 data for obesity drug ALN-2232 and three-to-four new IND filings by 2026 end, plus 30% of sales reinvested in R&D for sustainable breakthroughs.
When is the next earnings date for Alnylam Pharmaceuticals, Inc. (ALNY)?
Alnylam Pharmaceuticals (ALNY) is scheduled to report its next earnings on February 12, 2026, before the market opens. This release will cover the fourth quarter of 2025 (Q4 2025), ending December 31, 2025. Multiple sources align on this date as the consensus estimate, consistent with the company's historical mid-February pattern for year-end results.
Stock Performance Snapshot
Analyst Rating
Analysts suggest buying Alnylam Pharmaceuticals' stock with a target price of $495.04, indicating growth potential.
Financial Health
Alnylam Pharmaceuticals is generating strong profits and revenue, indicating a healthy financial position.
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Explore BasketWhy You’ll Want to Watch This Stock
RNAi platform potential
Alnylam’s GalNAc delivery platform enables targeted gene silencing across liver-related diseases, which could drive long-term growth, though clinical and commercial execution matters.
Clinical catalysts ahead
Late-stage trial readouts and new approvals can be material share-price catalysts; remember that trial or regulatory setbacks can also move the stock substantially.
Rare-disease reach
Market opportunity centres on rare, high‑need conditions where few therapies exist, but pricing, access and competition will influence commercial outcomes.
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