
Addex Therapeutics Ltd
Addex Therapeutics Ltd is a Switzerland-based clinical-stage pharmaceutical company. The Company focuses on development and commercialization of orally available small molecule drugs known as allosteric modulators for neurological disorders. The Company’s clinical programs pipeline include dipraglurant (mGlu5 NAM), which is Phase 2a placebo-controlled clinical trial for Parkinson's disease levodopa-induced dyskinesia (PD-LID), and is being prepared to enter registration trials for PD-LID, and ADX71149 (mGlu2 positive allosteric modulator or PAM), which is being developed in collaboration by its partner Janssen Pharmaceuticals, Inc to treat schizophrenia and anxious depression. It also is advancing several preclinical programs, including GABABPAM for pain, overactive bladder and other disorders, mGlu7 NAM for post-traumatic stress disorder, mGlu2 NAM for mild neurocognitive disorders, mGlu4 PAM for Parkinson’s disease and mGlu3 PAM for neurodegenerative disorders.
Stock Performance Snapshot
Financial Health
Addex Therapeutics is generating low revenue and has limited financial strength to support growth.
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Published: July 30, 2025
Explore BasketWhy You’ll Want to Watch This Stock
Allosteric approach
The company targets modulation of receptor activity rather than direct activation, an approach that may offer selectivity — though clinical benefit remains unproven.
Clinical catalysts ahead
Pipeline readouts and regulatory milestones can move the share price significantly; however, binary trial outcomes also increase downside risk.
Small‑cap dynamics
Low market capitalisation can mean higher volatility and limited liquidity, so position size and risk management are important for investors.
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