STRUCTURE THERAPEUTICS, INC.

STRUCTURE THERAPEUTICS, INC.

Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates.

Stock Performance Snapshot

Buy

Analyst Rating

Analysts recommend buying Structure Therapeutics' stock with a target price of $75.85, indicating strong potential growth.

Above Average

Financial Health

Structure Therapeutics is performing well, with strong cash flow and solid book value per share.

Source: Analyst sentiment is provided by Refinitiv Ltd, a global leader in financial market data with over 40k business clients. Refinitiv Ltd is an independent third party to Nemo. This is not advice.

Baskets Featuring GPCR

Pharma M&A Targets (Metabolic Disease Biotechs)

Pharma M&A Targets (Metabolic Disease Biotechs)

Novo Nordisk's $5.2 billion acquisition of Akero Therapeutics highlights a strategic push into the MASH treatment market. This deal could trigger a wave of similar acquisitions, boosting the value of other biotech firms with promising drugs for metabolic diseases.

Published: October 10, 2025

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MASH Stocks: Could Roche's Deal Spark More M&A?

MASH Stocks: Could Roche's Deal Spark More M&A?

Roche's $3.5 billion acquisition of 89bio for its liver disease drug highlights the growing MASH treatment market. This deal creates a potential tailwind for other biopharmaceutical companies developing therapies for liver and metabolic conditions.

Published: September 21, 2025

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Obesity Treatment (Pharma Giants vs Biotech Firms)

Obesity Treatment (Pharma Giants vs Biotech Firms)

Novo Nordisk's major restructuring, driven by intense competition from Eli Lilly, highlights the high-stakes battle in the weight-loss drug market. This theme focuses on other pharmaceutical companies that could benefit from this rivalry, either as innovators with next-generation treatments or as potential acquisition targets.

Published: September 10, 2025

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Cardio-Metabolic Drugs: Beyond Weight Loss Benefits

Cardio-Metabolic Drugs: Beyond Weight Loss Benefits

Following new data showing Novo Nordisk's Wegovy has superior cardiovascular benefits over a key rival, the competitive landscape for weight-loss drugs has intensified. This theme focuses on the pharmaceutical giants battling for dominance and the innovative biotechs whose research in related metabolic and cardiovascular fields is now more valuable than ever.

Published: September 1, 2025

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Beyond The Needle: The Oral GLP-1 Revolution

Beyond The Needle: The Oral GLP-1 Revolution

Eli Lilly's successful trial of its oral weight-loss drug, orforglipron, signals a major shift in the treatment landscape for obesity and diabetes. This theme focuses on the innovative pharmaceutical companies developing the next wave of convenient, non-injectable therapies poised to challenge the dominance of current market leaders.

Published: August 28, 2025

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Oral Obesity Treatments: Beyond The Needle

Oral Obesity Treatments: Beyond The Needle

Following successful Phase 3 trials for its oral weight-loss drug, orforglipron, Eli Lilly is positioned to enter the lucrative obesity treatment market. This development creates a new investment theme focused on pharmaceutical companies developing patient-friendly, oral alternatives to injectable GLP-1 therapies.

Published: August 27, 2025

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Which Pharma Stocks Could Follow Wegovy's Success?

Which Pharma Stocks Could Follow Wegovy's Success?

Following the FDA's approval of Novo Nordisk's Wegovy for a common liver disease, this theme focuses on pharmaceutical companies developing treatments for metabolic disorders. This development opens a new market for weight-loss drugs and signals opportunity for firms with therapies targeting related conditions.

Published: August 21, 2025

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GLP-1s Target Liver Disease

GLP-1s Target Liver Disease

The FDA's approval of Wegovy for a serious liver disease has boosted Novo Nordisk's market position and highlighted a major new application for GLP-1 drugs. This development creates an investment opportunity in companies focused on innovative treatments for metabolic and liver-related conditions.

Published: August 19, 2025

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The Global Weight-Loss Drug Price Shift

The Global Weight-Loss Drug Price Shift

Eli Lilly's significant price hike for Mounjaro in the UK, driven by U.S. political pressure, highlights a new global pricing strategy for blockbuster drugs. This creates a potential opportunity for competitors in the booming weight-loss market as patients and providers may seek more affordable alternatives.

Published: August 15, 2025

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Executive Conviction In The GLP-1 Market

Executive Conviction In The GLP-1 Market

Following a stock drop from a clinical trial setback, Eli Lilly executives made significant share purchases, signaling strong belief in the company's future. This insider confidence highlights a potential investment opportunity in the rapidly growing and competitive GLP-1 weight-loss drug market.

Published: August 13, 2025

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Next-Generation Drug Delivery Systems

Next-Generation Drug Delivery Systems

This carefully selected group of stocks represents innovative companies revolutionizing how medications are delivered to patients. Handpicked by our professional analysts, these firms are developing technologies that make treatments simpler, more effective, and user-friendly, creating meaningful investment potential in an evolving healthcare landscape.

Published: July 18, 2025

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Digital Therapeutics & Prescription Apps

Digital Therapeutics & Prescription Apps

Software is becoming the new medicine. These carefully selected companies are developing FDA-cleared applications that treat everything from mental health to diabetes. With growing insurance reimbursement and massive scalability, these digital treatments represent healthcare's next frontier.

Published: June 17, 2025

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Why You’ll Want to Watch This Stock

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Pipeline Catalysts Ahead

Clinical readouts and partnerships can move the share price; these events are worth watching, though outcomes and timing are uncertain.

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Small-cap Dynamics

With a market cap near $1.6bn, the company can offer growth potential but also higher volatility and funding sensitivity.

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Science-led Opportunity

Targeting GPCRs taps a large therapeutic area; scientific promise exists, but clinical success is not guaranteed and carries regulatory risk.

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6% Interest on Cash

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