Protagenic Therapeutics Inc

Protagenic Therapeutics Inc

Protagenic Therapeutics, Inc. is a neuroactive biopharmaceutical company. The Company has approximately six drug candidates targeting stress-related and CNS disorders, including treatments for obesity and metabolic disorders. The Company's pipeline includes PT-00114 in Phase I/IIa and five preclinical assets including PHYX-001, cannabinoid-based compounds, and modified stilbenoid assets. The PHYX-001 is a potassium channel modulator with a mechanism similar to XEN1101 and BHV-7000. The Company's cannabinoid assets include multiple cannabinoid-based compounds with composition-of-matter IP; potential in CNS, cardiometabolic, and other indications. The Company's cannabinoid assets also include a molecule with potential in the obesity, metabolic dysfunction sector, where the GLP-1 agonists have become medications. Its modified stilbenoid assets include modified stilbenoid compounds with composition-of-matter IP and anticonvulsant activity in preclinical models.

Stock Performance Snapshot

Above Average

Financial Health

Protagenic Therapeutics is showing positive cash flow and reasonable book value per share.

Source: Analyst sentiment is provided by Refinitiv Ltd, a global leader in financial market data with over 40k business clients. Refinitiv Ltd is an independent third party to Nemo. This is not advice.

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AbbVie's potential $1 billion acquisition of Gilgamesh Pharmaceuticals signals a major strategic investment in the mental health sector. This move is expected to increase M&A interest and valuations for other biotech firms developing innovative psychiatric therapies.

Published: July 31, 2025

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Why You’ll Want to Watch This Stock

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Microcap, high risk

With a market cap near $6M, the stock can be very volatile and thinly traded — potential gains come with a higher risk of loss and limited liquidity.

Binary catalyst profile

Value may hinge on clinical, regulatory or financing events that can move the share price sharply in either direction; outcomes are uncertain.

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Due diligence essentials

Review filings, cash runway and management track record; small biotechs often need further funding and carry execution risk.

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6% Interest on Cash

Earn 6% AER on uninvested cash with daily interest payments.

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