SCHOLAR ROCK HOLDING CORP
Scholar Rock Holding Corporation is a late-stage biopharmaceutical company. It is focused on advancing treatments for neuromuscular diseases, cardiometabolic disorders, and other serious diseases. Its transforming growth factor beta (TGFb) superfamily biology, its novel molecular mechanisms of growth factor activation enabled it to develop a proprietary platform for the discovery and development of monoclonal antibodies that locally and selectively target the precursor, or latent, forms of growth factors. Its product candidate, apitegromab, is a selective, fully human, monoclonal antibody, with a mechanism of action that results in inhibition of the activation of the growth factor, myostatin, in skeletal muscle. Apitegromab is being developed as a potential first muscle-targeted therapy for the treatment of SMA. Its products include SRK-439, SRK-181, SRK-373 and SRK-256. SRK-181 is a selective inhibitor of the activation of latent TGFb1, is being developed for the treatment of cancers.
Stock Performance Snapshot
Analyst Rating
Analysts recommend buying Scholar Rock Holding Corp's stock, expecting it to rise to $40.43.
Financial Health
Scholar Rock Holding Corp shows strong cash flow and a solid book value per share.
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Gene Therapy's Competitive Shift
The European Medicines Agency's recent rejection of Sarepta Therapeutics' gene therapy creates a potential opening for its competitors. This theme focuses on the biopharmaceutical companies that stand to benefit from this regulatory hurdle in the Duchenne muscular dystrophy market.
Published: July 25, 2025
Explore BasketWhy You’ll Want to Watch This Stock
Clinical-stage drug focus
The company’s value hinges on clinical readouts and scientific validation, which can create material share‑price moves; outcomes are uncertain.
Pipeline catalysts ahead
Upcoming trial milestones and partnerships can drive momentum, though any positive prospects may be offset by trial or regulatory disappointment.
Regulatory and cashflow
Regulatory approvals and financing decisions will shape long‑term prospects; investors should watch cash runway and funding plans carefully.
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