

VHT vs XLV
Two funds, one decision: we compare cost, performance and what each ETF actually holds in October 2026.
VHT tracks the MSCI US IMI 25/50 Health Care index with 424 holdings for a 0.09% expense ratio, while XLV tracks the S&P Health Care Select Sector index with 63 holdings for 0.08%. Both list the same ten largest stocks, led by Eli Lilly at 12.79% in VHT and 14.95% in XLV. VHT suits investors who want small-cap biotech included; XLV suits large-cap-only exposure. Educational content, not financial advice.
VHT tracks the MSCI US IMI 25/50 Health Care index with 424 holdings for a 0.09% expense ratio, while XLV tracks the S&P Health Care Select Sector index with 63 holdings for 0.08%. Both list the same ...
Investment Analysis

VHT
VHT
Pros
- 424 holdings span large, mid and small-cap healthcare, including smaller biotech
- Lower single-stock concentration, with Eli Lilly at 12.79% versus 14.95% in XLV
- Vanguard fund with a history back to January 2004
Considerations
- Expense ratio of 0.09% is a touch above XLV's 0.08%
- Smaller fund at about $19 billion in net assets compared with XLV's $43.5 billion
- Small-cap biotech exposure can add volatility without changing the top-heavy profile

XLV
XLV
Pros
- Expense ratio of 0.08%, about $8 a year per $10,000 invested
- About $43.5 billion in net assets and trading history since December 1998
- Pure large-cap exposure to the S&P 500 healthcare sector with 63 holdings
Considerations
- Only 63 holdings, so no exposure to mid or small-cap healthcare companies
- More concentrated, with Eli Lilly and Johnson & Johnson above 25% combined
- Dividend yield of 1.50% is essentially the same as VHT's 1.49%
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