PfizerModerna
Live Report · Updated April 27, 2026

Pfizer vs Moderna

Pfizer parlayed its pandemic windfall into a massive acquisition spree, while Moderna is still running hard to diversify beyond its mRNA COVID franchise before the revenue cliff steepens. Both compani...

Why It's Moving

Pfizer

Pfizer Analysts Cluster Around $28 Target Amid Mixed Buy-Hold Signals for 2026

  • RBC Capital's April 20 note set a $25 target, signaling downside risks tied to slower-than-expected oncology growth.
  • Consensus from 24-36 analysts leans toward neutral-to-buy with average targets of $28-$30, driven by steady dividend appeal and cost-cutting momentum.
  • High-end forecasts hit $36-$38, betting on blockbuster potential from new vaccines and rare disease therapies.
Sentiment:
⚖️Neutral

Investment Analysis

Pros

  • Pfizer maintains a wide economic moat from its established drug portfolio and brand strength.
  • Pfizer offers a high dividend yield of around 6.74% to shareholders.
  • Pfizer exhibits low stock volatility of approximately 5.6%, reducing price fluctuation risk.

Considerations

  • Pfizer anticipates a 23% decline in its COVID-19 business, pressuring 2026 revenues.
  • Pfizer faces a looming patent cliff on key best-selling drugs, risking revenue losses.
  • Pfizer trimmed its FY2026 profit forecast to $2.80-$3 per share, below analyst estimates.

Pros

  • Moderna projects 10% revenue growth for 2026, driven by pipeline advancements.
  • Moderna holds a healthy current ratio of 3.93, ensuring strong liquidity coverage.
  • Moderna anticipates key 2026 catalysts from its Phase III melanoma trial readout.

Considerations

  • Moderna reports high stock volatility of nearly 20%, increasing investment risk.
  • Moderna experienced a 56% revenue decline over the last twelve months with negative EBITDA.
  • Moderna shows a negative gross profit margin of -107.62%, indicating ongoing unprofitability.

Pfizer (PFE) Next Earnings Date

Pfizer's next earnings date is scheduled for May 5, 2026, before the market opens, covering Q1 2026 results. This follows the pattern of their prior Q4 2025 report on February 3, 2026. Investors should monitor for the conference call details around 10:00 AM ET.

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PFE
PFE$27.56
vs
MRNA
MRNA$53.72