
ALNYLAM PHARMACEUTICALS INC
Alnylam Pharmaceuticals (ALNY) is a biotechnology company that develops RNA interference (RNAi) therapeutics to silence disease-causing genes. Investors should know it has moved from research-stage to a commercial entity, with multiple approved medicines for rare genetic disorders — including treatments for hereditary ATTR amyloidosis, acute hepatic porphyria and primary hyperoxaluria — and a broad pipeline built on its GalNAc delivery platform. The business is growth-oriented: revenues depend on uptake of marketed drugs, pricing and successful launches of late-stage candidates. Key risks include trial outcomes, regulatory decisions, pricing pressures, manufacturing scale-up and competition from other modalities. With a market capitalisation near $62.13 billion, Alnylam may appeal to investors seeking exposure to innovative therapeutics, but it suits those comfortable with biotech volatility. This is general information for educational purposes only and not personalised investment advice; values can fall as well as rise.
Why It's Moving

Needham Boosts ALNY Price Target on Robust 2026 Sales Outlook Signaling Biotech Momentum.
- Needham lifted target to $529 from $520 with Buy rating intact, driven by 2026 product sales forecast of $4.9-5.3B beating consensus by over $400M.
- TTR sales guidance of $4.4-4.7B tops estimates by 7%, highlighting strength in flagship drugs like Amvuttra amid expanding cardiomyopathy indications.
- Analysts flock to Strong Buy consensus, with recent upgrades reflecting optimism over 53% revenue growth and key 2026 launches.

Needham Boosts ALNY Price Target on Robust 2026 Sales Outlook Signaling Biotech Momentum.
- Needham lifted target to $529 from $520 with Buy rating intact, driven by 2026 product sales forecast of $4.9-5.3B beating consensus by over $400M.
- TTR sales guidance of $4.4-4.7B tops estimates by 7%, highlighting strength in flagship drugs like Amvuttra amid expanding cardiomyopathy indications.
- Analysts flock to Strong Buy consensus, with recent upgrades reflecting optimism over 53% revenue growth and key 2026 launches.
When is the next earnings date for ALNYLAM PHARMACEUTICALS INC (ALNY)?
Alnylam Pharmaceuticals (ALNY) is scheduled to report its next earnings on April 30, 2026, before the market opens, with a conference call at 8:30 AM ET. This release will cover the first quarter of 2026, ending March 31, 2026. The prior quarter's results were reported on February 12, 2026, aligning with the company's typical late-month pattern for quarterly disclosures.
Stock Performance Snapshot
Analyst Rating
Analysts suggest buying Alnylam Pharmaceuticals' stock with a target price of $495.04, indicating growth potential.
Financial Health
Alnylam Pharmaceuticals is generating strong profits and revenue, indicating a healthy financial position.
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Explore BasketWhy You’ll Want to Watch This Stock
RNAi platform potential
Alnylam’s GalNAc delivery platform enables targeted gene silencing across liver-related diseases, which could drive long-term growth, though clinical and commercial execution matters.
Clinical catalysts ahead
Late-stage trial readouts and new approvals can be material share-price catalysts; remember that trial or regulatory setbacks can also move the stock substantially.
Rare-disease reach
Market opportunity centres on rare, high‑need conditions where few therapies exist, but pricing, access and competition will influence commercial outcomes.
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