Alnylam Pharmaceuticals, Inc.
Alnylam Pharmaceuticals (ALNY) is a biotechnology company that develops RNA interference (RNAi) therapeutics to silence disease-causing genes. Investors should know it has moved from research-stage to a commercial entity, with multiple approved medicines for rare genetic disorders — including treatments for hereditary ATTR amyloidosis, acute hepatic porphyria and primary hyperoxaluria — and a broad pipeline built on its GalNAc delivery platform. The business is growth-oriented: revenues depend on uptake of marketed drugs, pricing and successful launches of late-stage candidates. Key risks include trial outcomes, regulatory decisions, pricing pressures, manufacturing scale-up and competition from other modalities. With a market capitalisation near $62.13 billion, Alnylam may appeal to investors seeking exposure to innovative therapeutics, but it suits those comfortable with biotech volatility. This is general information for educational purposes only and not personalised investment advice; values can fall as well as rise.
Why It's Moving
Needham Boosts ALNY Target on Stellar 2026 Guidance Signaling Biotech Momentum.
- 2026 total product sales guidance of $4.9-5.3 billion topped consensus estimates, implying accelerated adoption of RNAi therapies in rare diseases.
- Q4 2025 product revenue hit $996 million, nearly matching analyst forecasts and underscoring 53% year-over-year growth despite a slight Amvuttra miss.
- Amvuttra launch in TTR-CM flagged as a major 2026 catalyst, with TTR sales projected 7% above consensus for heightened competitive edge.
Needham Boosts ALNY Target on Stellar 2026 Guidance Signaling Biotech Momentum.
- 2026 total product sales guidance of $4.9-5.3 billion topped consensus estimates, implying accelerated adoption of RNAi therapies in rare diseases.
- Q4 2025 product revenue hit $996 million, nearly matching analyst forecasts and underscoring 53% year-over-year growth despite a slight Amvuttra miss.
- Amvuttra launch in TTR-CM flagged as a major 2026 catalyst, with TTR sales projected 7% above consensus for heightened competitive edge.
When is the next earnings date for Alnylam Pharmaceuticals, Inc. (ALNY)?
Alnylam Pharmaceuticals' next earnings announcement is scheduled for April 29-30, 2026, with the most commonly cited date being April 30, 2026. This report will cover the company's Q1 2026 financial results. The earnings call is expected to occur at 8:30 AM ET on the announcement date, where management will discuss financial performance and forward guidance.
Stock Performance Snapshot
Analyst Rating
Analysts suggest buying Alnylam Pharmaceuticals' stock with a target price of $495.04, indicating growth potential.
Financial Health
Alnylam Pharmaceuticals is generating strong profits and revenue, indicating a healthy financial position.
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Explore BasketWhy You’ll Want to Watch This Stock
RNAi platform potential
Alnylam’s GalNAc delivery platform enables targeted gene silencing across liver-related diseases, which could drive long-term growth, though clinical and commercial execution matters.
Clinical catalysts ahead
Late-stage trial readouts and new approvals can be material share-price catalysts; remember that trial or regulatory setbacks can also move the stock substantially.
Rare-disease reach
Market opportunity centres on rare, high‑need conditions where few therapies exist, but pricing, access and competition will influence commercial outcomes.
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